Government Contract Reports

  • Knafla, A., Campbell, J., Wilson, R., Healey, N., Kennepohl, E. 2011. Evaluation of Potential Effects of Short-Term Exposure to Substances at Contaminated Sites and Development of Recommendations on Exposure Amortization for Non-Carcinogenic Substances. Prepared for Health Canada under contract to Health Canada.

  • Healey, N., H. Jones‐Otazo, M. Walker & A. Knafla. 2010. Toxicological Review and Recommended 10 Toxicological Reference Values for Environmental Lead Exposure in Canada. FINAL REPORT. 11 Prepared under contract to Health Canada. Prepared for the Contaminated Sites Division, Safe 12 Environments Directorate, Healthy Environment and Consumer Safety Branch, Health Canada, 13 Ottawa.

  • Knafla, A. 2010. Review and Update of the Document Canadian Soil Quality Guidelines for Contaminated Sites – Human Health Effects: Inorganic Lead (1996 Report) and Derivation of Human Health-Based Indoor Settled Dust Screening Concentrations for Inorganic Lead. Prepared for Health Canada under contract to Health Canada.

  • Knafla, A., Campbell, J. 2010/2009. Pilot Study for Biomonitoring of Arsenic (As) Species in Rural Nova Scotia Communities. Sample collection and assessment of levels of genetic damage via Comet and Micronuclei assay. Prepared for Health Canada under contract to Health Canada.

  • Guernsey, J., Knafla, T., Gibson, M., Parsons, M., King, G., Dabek-Zlotorzynska, E., Celo, V. 2009. Project Title: A Pilot Study of the Off-Site Transport of Arsenic Associated Fugitive PM2.5 Emissions from Montague Gold Mine Tailings, Nova Scotia on Communities Directly Downwind of the Site. Prepared for Health Canada under contract to Health Canada.

  • Knafla, A., Wilson, R., Carey, J. 2009. Toxicity Review of Low Boiling Point Naphthas (LBPNS) for the Petroleum Sector, Chemical Management Plan, Health Canada. Prepared for Health Canada under contract to Health Canada.

  • Knafla, A., Wilson, R., Carey, J. 2009. Toxicity Review of Gas Oils for the Petroleum Sector, Chemical Management Plan, Health Canada. Prepared for Health Canada under contract to Health Canada.

  • Knafla, A., Wilson, Kennepohl, E., R., Carey, J. 2009. Toxicity Review of Aromatic Extracts for the Petroleum Sector, Chemical Management Plan, Health Canada. Prepared for Health Canada under contract to Health Canada.

  • Carey, J., Knafla, A. 2009. Development of a Developmental Toxicity Database for Health Canada. Prepared for Health Canada under contract to Health Canada.

  • Knafla, A. 2008. Critical Review of Potential Health Effects Associated with Lead (Pb) Final Report. (Prepared for Health Canada under subcontract to URS Canada Inc. HECS-SEP-BC/Yukon 05/06-22).

  • Knafla, A., Carey, J. 2008. Toxicokinetics of Methyl Mercury. (Prepared for Health Canada under subcontract to GlobalTox International Consultants Inc., 2008).

  • Knafla, A., Carey, J. 2008. Lead (Pb) Toxicokinetic Modeling in Support of the Development of a Toxicity Reference Value. (Prepared for Health Canada under subcontract to GlobalTox International Consultants Inc., 2008).

  • Brecher, R.W., T. Knafla, A. Iglesias and J. Carey. 2008. Pharmacokinetics and Toxicology of Inorganic Mercury. Prepared for Health Canada, Bureau of Risk and Impact Assessment. March, 2008).

  • Knafla, A., Carey, J. 2008. Development of a Serum Toxicity Reference Value for Perfluorooctanoic Acid (PFOA) (prepared on the behalf of Health Canada via subcontract to URS Canada Inc., 2008).

  • Knafla, A., Carey, J. 2008. Qualitative Human Exposure Assessment Framework for Arsenic in Nova Scotia. Prepared under contract to Health Canada, Halifax, NS.

  • Ranganathan, S., Knafla, A. 2008. Development of an Ecological Soil Quality Guideline for n-hexane. Prepared for and under contract to Alberta Environment.

  • Ranganathan, S., Knafla, A. 2008. Development of Ecological Soil Quality Guideline for n-hexane. Prepared for and under contract to Health Canada.

  • Knafla, A., Ott, C., Carey, J. 2007. Preparation of a Supporting Document for Development of Uncertainty and Modifying Factors for Mercury Vapour (Toxicological Reference Value Section) - In Support of: Scientific Criteria Document for Mercury Vapour (Hg0) (Prepared on the behalf of Health Canada via subcontract to URS Canada Inc.).

  • Carey J and Knafla A. 2007. Development of a toxicological profile for bisphenol A and interim toxicity reference value for consideration by Health Canada. Equilibrium Environmental Inc. August 2007.

  • Carey, J., Knafla, A. 2007. State of the Science Report for a Screening Health Assessment - Perfluorooctanoic Acid (PFOA), its Salts, and its Precursors that Contain the C8F15COOH Moiety. (prepared on the behalf of Health Canada via subcontract to URS Canada Inc. in 2007).

  • Knafla, A. 2007. Development of an Updated Carcinogenicity Slope Factor Value for Arsenic (completed on behalf of Health Canada under subcontract to URS Canada with contractual specifications that the carcinogenicity work be completed by Anthony Knafla).

  • Knafla, A., Ott, C., Petrovic, S., Ramji, S., Rowat, C., D. Schoen. 2006. Importance of Carcinogenic Alkyl Substituted and High Molecular Weight Polycyclic Aromatic Hydrocarbons at Contaminated Sites and Update of Toxic Equivalency Factors for Hydrocarbon Mixtures. Book of Abstracts - 2006 Health Canada Science Forum Proceedings.

  • Knafla, A., Wilson, R. 2006. Preliminary examination of vapour concentration thresholds for adverse effects on the human respiratory system and/or mucosal irritation, and comparison with the existing CCME TRV of 18.4 mg/m3 for the F1 C6 to C8 aliphatic hydrocarbons. Memorandum prepared for CCME Soil Quality Guidelines Task Group Toxicity Reference Value Subgroup. Prepared by A. Knafla (Equilibrium Environmental Inc.) and R. WIlson (Wilson Scientific Inc.). February 7, 2006.

  • Knafla, A. URS Canada Inc., Equilibrium Environmental Inc. 2006. Effects of Lead - Critical review of potential health effects of lead and analysis of oral dose of blood kinetic for determination of lead tolerable daily intake. Contractor report prepared for Health Canada. Burnaby, BC.

  • Knafla, A. Equilibrium Environmental Inc. (Equilibrium). 2005. Critical Review and Evaluation of Toxicological Reference Values for Petroleum Hydrocarbon Sub-fractions within Fractions F2, F3 and F4. Report prepared for Environmental Protection Branch, Health Canada, Burnaby, BC. March 29. 8-94

  • Knafla, A. Equilibrium Environmental Inc. (Equilibrium). 2005. Evaluation of Issues Related to the Development of Updated Petroleum Hydrocarbon Constituent Toxicity Reference Values and Development of an Updated Toxicity Reference Value for C6 to C8 Aliphatic Hydrocarbons. Report prepared in association with GlobalTox Toxicology Focused Solutions and Wilson Scientific Consulting Inc. for Environmental Protection Branch, Health Canada, Burnaby BC. April 25.

  • Knafla, A., R.W. Brecher and R. Wilson. 2004. Gamma-Diketone-like Toxicity of Components of the F1 Fraction of Petroleum Hydrocarbons. Prepared for Health Canada.

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